Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01
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چکیده
منابع مشابه
Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01
Viral infections can affect the glycosylation pattern of glycoproteins involved in antiviral immunity. Given the importance of protein glycosylation for immune function, we investigated the effect that modulation of the highly conserved HLA class I N-glycan has on KIR:HLA interactions and NK cell function. We focused on HLA-B*57:01 and its interaction with KIR3DL1, which has been shown to play ...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0145324